Peflin injection
WebJun 8, 2016 · Peflin depletion increases ER-to-Golgi transport. To clarify the role of PEF proteins in secretion, we depleted peflin from normal rat kidney (NRK) cells using siRNA … WebJun 8, 2016 · Peflin depletion increases ER-to-Golgi transport To clarify the role of PEF proteins in secretion, we depleted peflin from normal rat kidney (NRK) cells using siRNA …
Peflin injection
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WebMay 1, 2024 · Keflin may be given intravenously or by deep intramuscular injection into a large muscle mass, such as the gluteus or lateral aspect of the thigh, to minimise pain … WebJun 21, 2024 · Penile injections are intended for any person who has issues with becoming erect, achieving enough stiffness for penetrative sex, or keeping an erection for the desired length of time. People...
WebMar 1, 2002 · ALG-2 (apoptosis-linked gene-2 protein) and peflin are Ca 2+-binding proteins and belong to the penta-EF-hand (PEF) protein family, which includes calpain, sorcin, and grancalcin.ALG-2 forms either a homodimer or a heterodimer with peflin like other PEF proteins. In this study, we found that the fifth-EF-hand (EF-5) regions of both ALG-2 and … WebApr 7, 2006 · Peflin and ALG2 colocalized in the cytoplasm, but ALG2 was also detected in nuclei, as revealed by immunofluorescence staining and subcellular fractionation. Peflin was recovered in the cytosolic fraction in the absence of Ca (2+) and in the membrane/cytoskeletal fraction in the presence of Ca (2+).
WebHGNC:30009. General References. Kitaura Y, Watanabe M, Satoh H, Kawai T, Hitomi K, Maki M: Peflin, a novel member of the five-EF-hand-protein family, is similar to the apoptosis-linked gene 2 (ALG-2) protein but possesses nonapeptide repeats in the N-terminal hydrophobic region. Biochem Biophys Res Commun. 1999 Sep 16;263 (1):68-75. WebHowever, here we demonstrate that penta-EF hand (PEF) proteins ALG-2 and peflin constitute a hetero-bifunctional COPII regulator that responds to Ca 2+ signaling by …
WebApr 16, 2024 · ALG-2:peflin expression ratio can modulate ER export rates up or down by 107% of the basal rate. Through their ALG-2 subunit, ALG-2-peflin hetero-oligomers are shown to bind ERES to inhibit ER export of multiple cargo types, including collagen I. Conversely, without peflin, ALG-2 binds ERES to stimulate ER export.
WebJul 29, 2024 · Common subcutaneous injection sites include: the outer side or back of the upper arm the front and outer side of the upper thigh the belly area Intraosseous injections Intraosseous injections... how to grow citrus from seedsWebApr 16, 2024 · Penta EF-hand (PEF) proteins apoptosis-linked gene 2 (ALG-2) and peflin are cytoplasmic Ca2+ sensors with emerging functions in secretion. Here we demonstrate that adjustment of the ALG-2:peflin … john toomey tetra techWebJun 8, 2016 · Peflin depletion causes increased ALG-2 interactions with sec31A. (A) Whole cell CHAPS extracts of control and peflin knockdown NRK cells were subjected to immunoprecipitation with IgG- or anti ... how to grow citrus trees in cold climatesWebNov 8, 2024 · Peflin expression levels determine ER-to-Golgi transport rates over a wide dynamic range in an ALG-2-dependent manner To investigate the dynamic range and functional interactions of PEF protein regulation of ER export, we forced individual, tandem, or reciprocal expression changes of the two proteins. how to grow citrus rhsWebMay 17, 2003 · The cDNA encoding ALG-2, ALG-2,1, peflin, the 82 amino acid long C-terminal part of peflin (deltapeflin), grancalcin, sorcin, calpain small and large subunits were inserted into the pBDGAL4 and pADGAL4 vectors and expressed pairwise in the YRG-2 yeast strain. The interaction phenotype of the transformed yeast was analyzed by filter lift assay. how to grow cinnamon treeWebApr 27, 2001 · Peflin, a newly identified 30-kDa Ca(2+)-binding protein, belongs to the penta-EF-hand (PEF) protein family, which includes the calpain small subunit, sorcin, … how to grow clawsWebFind user ratings and reviews for Keflin injection on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction how to grow clematis little lemons