Digoxin interstage mortality
WebNov 16, 2012 · Interstage mortality for those not on digoxin was 12.3%, compared to 2.9% among those on digoxin, with an adjusted hazard ratio of 3.5 (95% CI, 1.1–11.7; P=0.04). The number needed to treat to ... WebMar 18, 2024 · Digoxin is used for the treatment of heart failure in pediatric patients and acts by controlling numerous functions of the cardiovascular system. Digoxin use in single ventricle congenital heart disease may decrease interstage mortality. The study will be conducted in approximately 48 subjects at approximately 13 investigational centers.
Digoxin interstage mortality
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WebMar 6, 2024 · Patients with a serum digoxin concentration ≥1.2 ng/ml had a 56% increased hazard of mortality (adjusted HR, 1.56; 95% confidence interval [CI], 1.20–2.04). When analyzed as a continuous variable, serum digoxin concentration was associated with a 19% higher adjusted hazard of death for each 0.5 ng/ml increase (p = 0.0010); these results ... WebDec 1, 2024 · The impact of digoxin on interstage mortality remains unproven. Abstract. The use of Digoxin has been associated with improved interstage survival following …
WebQuality improvement efforts have focused on reducing interstage mortality for infants with hypoplastic left heart syndrome (HLHS). In 1/2016, two publications reported that use of digoxin was associated with reduced interstage mortality. The degree to which these findings have affected real world pr … WebOct 1, 2024 · Interstage mortality is poorly understood and remains a high-risk period for patients with SVCHD. We present a validated risk score to predict interstage mortality that identified moderate or greater TR and a persistent supplemental O 2 requirement as the greatest risk subgroup. Interstage mortality may be impacted by intensifying …
WebThe protective effect of digoxin for interstage mortality, despite an unclear therapeutic mechanism, has been reported in several studies [9, 17,32]. Based largely on these reports, the use of ... WebMay 4, 2024 · Effect of Digoxin on Interstage Outcomes following Stage I Palliation for Functionally Univentricular Hearts: A Systematic Review and Meta-Analysis May 2024 DOI: 10.1101/2024.05.04.22274522
WebApr 11, 2024 · cardiac function , digoxin , echocardiogram , interstage mortality , interstage period , single-ventricle congenital heart disease Search for Similar Articles …
WebDigoxin has been associated with reduced interstage mortality after Norwood procedure. We sought to determine its association with survival and change in weight-for-age Z-score (WAZ) before the ... explorer park indianapolisWebSerum digoxin concentration (SDC) data were infrequently considered, but available data suggested a greater association between increasing SDC and all-cause mortality. This … bubble guppies mia cryingWebInterstage mortality was 9.4%. Digoxin use was associated with lower risk of death (P =.03) on univariable analysis, however no single medication was an independent predictor on regression analysis. Change in weight-for-age z-score was studied as outcome of somatic growth with 36.3% patients showing a decrease during the interstage period. bubble guppies miss goo gooWebMay 15, 2024 · Multivariable models for propranolol versus digoxin for mortality (A), cost (B) ... Association of digoxin with interstage mortality: results from the pediatric heart network single ventricle reconstruction trial public use dataset. J … explorer package in rWebFeb 2, 2024 · Quality improvement efforts have focused on reducing interstage mortality for infants with hypoplastic left heart syndrome (HLHS). In 1/2016, two publications reported that use of digoxin was associated with reduced interstage mortality. The degree to which these findings have affected real world practice has not been evaluated. The discharge … explorer parka - women\\u0027sWebIn the digoxin group, there was a trend toward a decrease in the risk of death attributed to worsening heart failure (risk ratio, 0.88; 95 percent confidence interval, 0.77 to 1.01; P = 0.06 ... explorer pass for scotlandWebJan 26, 2016 · Interstage mortality for those not on digoxin was 12.3%, compared to 2.9% among those on digoxin, with an adjusted hazard ratio of 3.5 (95% CI, 1.1–11.7; P=0.04). The number needed to treat to ... bubble guppies milk the cow fandom